Product Name |
Tandutinib - API
|
Product Code |
DA-T332-a
|
Chemical name |
Tandutinib
|
Synonyms |
4-[6-Methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethoxy)phenyl]-1-piperazinecarboxamide; [4-[6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl]piperazinyl]-N-[4-(methylethoxy)phenyl]carboxamide; 1-Piperazinecarboxamide, 4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethoxy)phenyl]-;
|
Impurity |
NA
|
CAS Number |
387867-13-2
|
Alternate CAS # |
NA
|
Molecular form |
C31H42N6O4
|
Appearance |
White to Off-White Solid
|
Melting Point |
NA
|
Mol. Weight |
562.72
|
Storage |
2-8°C Refrigerator
|
Solubility |
NA
|
Stability |
NA
|
Category |
impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
|
Boiling Point |
NA
|
Applications |
An oral, small-molecule inhibitor of FLT3 for the treatment of AML (acute myelogenous leukemia) and other cancer indications. The drug exhibited limited activity as a single agent in phase I and II clinical trials in patients with AML and myelodysplastic syndrome, but displayed promising antileukemic activity (90% complete remissions) in a phase I/II trial in patients with newly diagnosed AML when administered in combination with cytarabine and daunorubicin.
|
Dangerous Goods Info |
NA
|
References |
NA
|
Extra Notes |
NA
|
Documents (MSDS) |
No Data Available
|
Keywords |
NA |