1-(2-Iodoethyl)-2-octylbenzene
Product Name |
1-(2-Iodoethyl)-2-octylbenzene
|
Product Code |
DA-F035-bg
|
Chemical name |
1-(2-Iodoethyl)-2-octylbenzene
|
Synonyms |
2-Octylphenethyl iodide;
|
Impurity |
NA
|
CAS Number |
162358-96-5
|
Alternate CAS # |
NA
|
Molecular form |
C16H25I
|
Appearance |
NA
|
Melting Point |
NA
|
Mol. Weight |
344.28
|
Storage |
2-8°C Refrigerator
|
Solubility |
NA
|
Stability |
NA
|
Category |
intermediates,impurities,metabolites,pharmaceutical standards,Fine Chemicals
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Boiling Point |
NA
|
Applications |
1-(2-Iodoethyl)-2-octylbenzene is an impurity of Fingloimod (F805000), also known as FTY720. FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
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Dangerous Goods Info |
NA
|
References |
NA
|
Extra Notes |
NA
|
Documents (MSDS) |
No Data Available
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Keywords |
NA |