Product Name | Aminopterin-α-hyrazide |
Product Code | DA-M072-y |
Chemical name | Aminopterin-α-hyrazide |
Synonyms | N5-Amino-N2-(4-((2,4-diaminopteridin-6-yl)(methyl)amino)benzoyl)-L-glutamine; |
Impurity | NA |
CAS Number | 118359-33-4 |
Alternate CAS # | NA |
Molecular form | C19H22N10O4 |
Appearance | NA |
Melting Point | NA |
Mol. Weight | 454.45 |
Storage | 2-8°C Refrigerator |
Solubility | NA |
Stability | NA |
Category | impurities,metabolites,pharmaceutical standards,intermediates,fine chemicals |
Boiling Point | NA |
Applications | Aminopterin-α-hyrazide, is derivative of Aminopterin (A628850), which is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity. |
Dangerous Goods Info | NA |
References | NA |
Extra Notes | NA |
Documents (MSDS) | No Data Available |
Keywords | NA |