Product Name |
Revefenacin - API
|
Product Code |
DA-R135-a
|
Chemical name |
Revefenacin
|
Synonyms |
Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[2-[[4-[[4-(aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl ester; 1-[2-(1-{4-[(4-Carbamoylpiperidin-1-yl)methyl]phenyl}-N-methylformamido)ethyl]piperidin-4-yl N-{[1,1'-biphenyl]-2-yl}carbamate;
|
Impurity |
NA
|
CAS Number |
864750-70-9
|
Alternate CAS # |
NA
|
Molecular form |
C35H43N5O4
|
Appearance |
NA
|
Melting Point |
NA
|
Mol. Weight |
597.76
|
Storage |
2-8°C Refrigerator
|
Solubility |
NA
|
Stability |
NA
|
Category |
impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
|
Boiling Point |
NA
|
Applications |
Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LABA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic clearance and minimizing of the systemically mediated adverse reactions. The LABA group falls into a parent category known as long-acting inhaled bronchodilators and this type of agents are recommended as a maintenance therapy for chronic obstructive pulmonary disease (COPD).1 From the LABA group, revefenacin is the first once-daily nebulized LAMA treatment.2 It was developed by Theravance Biopharma and FDA approved on November 9, 2018.8
|
Dangerous Goods Info |
NA
|
References |
NA
|
Extra Notes |
NA
|
Documents (MSDS) |
No Data Available
|
Keywords |
NA |