Product Name |
(1S,2R)-Bortezomib-d5
|
Product Code |
DA-B169-56
|
Chemical name |
(1S,2R)-Bortezomib-d5
|
Synonyms |
B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid-d5;
|
Impurity |
NA
|
CAS Number |
NA
|
Alternate CAS # |
NA
|
Molecular form |
C19H20D5BN4O4
|
Appearance |
NA
|
Melting Point |
NA
|
Mol. Weight |
389.27
|
Storage |
2-8°C Refrigerator
|
Solubility |
NA
|
Stability |
NA
|
Category |
chiral standards,boron derivatives,enzyme inhibitors,pharmaceutical standards,intermediates,fine chemicals,stable isotopes
|
Boiling Point |
NA
|
Applications |
Isotope labelled (1S,3R)-Bortezomib is an diastereomer of Bortezomib, the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
|
Dangerous Goods Info |
NA
|
References |
NA
|
Extra Notes |
NA
|
Documents (MSDS) |
No Data Available
|
Keywords |
NA |