Product Name |
BMS 599626-d4
|
Product Code |
DA-B159-01
|
Chemical name |
BMS 599626-d4
|
Synonyms |
N-[4-[[1-[(3-Fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic Acid (3S)-3-Morpholinylmethyl-d4 Ester; AC 480-d4;
|
Impurity |
NA
|
CAS Number |
1330172-72-9
|
Alternate CAS # |
NA
|
Molecular form |
C27H23D4FN8O3
|
Appearance |
NA
|
Melting Point |
NA
|
Mol. Weight |
534.58
|
Storage |
2-8°C Refrigerator
|
Solubility |
NA
|
Stability |
NA
|
Category |
aromatics,heterocycles,enzyme inhibitors,pharmaceutical standards,intermediates,fine chemicals,stable isotopes
|
Boiling Point |
NA
|
Applications |
It is a highly selective and potent inhibitor of HER1 and HER2 kinases and inhibits tumor cell proliferation through modulation of receptor signaling. BMS-599626 inhibits HER1/HER2 receptor heterodimerization and provides an additional mechanism of inhibiting tumors in which receptor coexpression and heterodimerization play a major role in driving tumor growth.
|
Dangerous Goods Info |
NA
|
References |
NA
|
Extra Notes |
NA
|
Documents (MSDS) |
No Data Available
|
Keywords |
NA |