Product Name |
4-Hydroxydebrisoquine
|
Product Code |
DA-D045-01
|
Chemical name |
4-Hydroxydebrisoquine
|
Synonyms |
2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-4-hydroxy; 4-Hydroxy-3,4-dihydroisoquinoline-2(1H)-carboximidamide;
|
Impurity |
NA
|
CAS Number |
59333-79-8
|
Alternate CAS # |
NA
|
Molecular form |
C10H13N3O
|
Appearance |
NA
|
Melting Point |
NA
|
Mol. Weight |
191.23
|
Storage |
2-8°C Refrigerator
|
Solubility |
NA
|
Stability |
NA
|
Category |
impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
|
Boiling Point |
NA
|
Applications |
An adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
|
Dangerous Goods Info |
NA
|
References |
NA
|
Extra Notes |
NA
|
Documents (MSDS) |
No Data Available
|
Keywords |
NA |